Allele Frequency Calculator
Enter Population Counts
For a single gene with two alleles (A and a)
Allele Frequency Results
Hardy-Weinberg Equilibrium Check
The observed genotype frequencies match the expected Hardy-Weinberg frequencies within a margin of error of 0.01.
Chi-square test: χ² = 0.042, p > 0.05. The population appears to be in Hardy-Weinberg equilibrium.
About Allele Frequencies
- For a diploid gene locus with two alleles (A and a), the Hardy-Weinberg principle states that p² + 2pq + q² = 1
- p represents the frequency of the dominant allele A, and q represents the frequency of recessive allele a
- p + q = 1, meaning the allele frequencies must sum to 1
- p² represents the frequency of homozygous dominant (AA)
- 2pq represents the frequency of heterozygous (Aa)
- q² represents the frequency of homozygous recessive (aa)
- A population in Hardy-Weinberg equilibrium is not evolving and shows no genetic drift, selection, mutation, or migration
Understanding the Allele Frequency Calculator
The allele frequency calculator is a handy tool for anyone studying genetics. It helps you determine the frequency of different alleles in a population. This calculator can be especially useful for students and researchers who want to analyse genetic data. With its simple interface, you can input various values to get quick results.
How to Use the Calculator
You can use the calculator in three main ways. First, you can enter genotype counts, which gives you information based on the number of individuals with specific genotypes. Second, if you know the frequency of one allele, you can use that to find out Other frequencies. Third, for advanced users, the calculator offers options for population genetics, allowing for more complex analyses.
Genotype Counts: A Simple Approach
When entering genotype counts, you will input numbers for three categories: Dominant Homozygous, Heterozygous, and Recessive Homozygous. This method is straightforward and provides immediate results about allele frequencies. Here’s what you need to enter:
- Dominant Homozygous (AA)
- Heterozygous (Aa)
- Recessive Homozygous (aa)
Using Known Frequencies
If you already have information about the frequency of an allele, this method is perfect for you. You can choose from several options, like the frequency of the dominant allele or the homozygous recessive genotype. Inputting a known frequency allows the calculator to determine the other allele frequencies based on the Hardy-Weinberg principle.
Advanced population genetics analysis
This section caters to users looking for a deeper analysis. It lets you input the initial frequency of the dominant allele and Fitness values for different genotypes. This helps to model how allele frequencies might change over generations. If you're studying evolutionary Biology, this feature can be quite insightful.
Results You Can Trust
Once you've entered your data, the calculator provides detailed results. You’ll see the population Statistics, including sample size and allele counts. Plus, it will show you the frequencies of both alleles (A and a) and the expected genotype frequencies. Understanding these results can help you draw conclusions about genetic variations in populations.
Visualising Genotype Distribution
The calculator also offers visual representations of genotype frequencies. Charts can help illustrate how different genotypes distribute within a population. Such visuals make it easier to understand the data at a glance, especially for presentations or assignments.
Learning About Allele Frequencies
The Allele Frequency Calculator is not just about numbers; it’s also about learning. It includes helpful information about the Hardy-Weinberg principle, explaining the relationships between alleles and genotypes. Understanding these concepts will strengthen your grasp of population genetics and evolutionary biology.
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